MPD work at MIT

MPD work at MIT is presented in the form of the view-graphs. The following subject areas are covered: the MIT program, its goals, achievements, and roadblocks; quasi one-dimensional modeling; two-dimensional modeling - transport effects and Hall effect; microscopic instabilities in MPD flows and modified two stream instability; electrothermal stability theory; separation of onset and anode depletion; exit plane spectroscopic measurements; phenomena of onset as performance limiter; explanations of onset; geometry effects on onset; onset at full ionization and its consequences; relationship to anode depletion; summary on self-field MPD; applied field MPD - the logical growth path; the case for AF; the challenges of AF MPD; and recommendations

Towards an appropriate comprehension of innovation sources in agrifood cooperatives

The existing typologies of innovation sources rely on classification criterions which are excessively generalist and developed under the consideration of private owned organisations. The present paper seeks to shed light on the special structural and operative features of agrifood cooperatives demanding a more comprehensive classification of innovation sources. A sample from the agrifood cooperative industry was selected as the scenario of the empirical research. Findings reveal a classification proposal of innovation sources into four differentiated groups (managers, technology, market and normative context) with regard to the management orientation of change (strategic vs. technical/legal) and the strength motivating the innovation (internal vs. external).Agrifood cooperatives, innovation sources, Agricultural and Food Policy, Q13.,

Synergistic growth factor microenvironments

Growth factors (GF) are remarkably powerful signalling molecules that orchestrate developmental biology. GFs are currently used in medjcal applications with limited success but it is clear that if their potential can be harnessed for biomedicine then they could underpin the discipline of regenerative medicine. However, while we understand that biology uses cell-secreted growth factors tethered to the ECM, biologists typically employ GFs in soluble format at high concentrations. When used in vivo, this causes off-target, unwanted effects, which severely limits their use. There is a vast amount of literature dealing with material systems that control the delivery of GFs. However, it was soon observed that GFs could be more effectively presented bound to surfaces from a solid-phase state rather than in soluble form, recapitulating the way the extracellular matrix (ECM) binds GFs. In parallel, evidence was found that within the ECM, GFs can actually work in cooperation with integrins and that this produced ehnaced GF signalling due to the crosstalk between both receptors. Recently this knowledge was used to engineer microenvironments that target simultaneous integrin and GF receptor engagement seeking to maximise GF effects in vitro (e.g. in terms of stem cell differentiation) but also tissue repair in vivo (e.g. bone regeneration and wound healing). This feature article introduces the concept of synergistic GF/integrin signalling and then introduces GF delivery systems that were key in the development of more advanced synergistic growth factor microenvironments

Coherent modes of X-ray beams emitted by undulators in new storage rings

Synchrotron radiation emitted by electrons passing through an undulator placed in a storage ring is decomposed in coherent modes. The case of ultimate storage rings where the electron emittance is comparable to the emittance of the photon fan is analyzed by means of the cross spectral density and the coherent mode spectrum. The proposed method permits naturally the statistical analysis and propagation of the cross spectral density along the beamline optics. The coherence properties of the X-ray beam at any point of the beamline are completely given in terms of the eigenvalues and coherent modes of the cross spectral density.Comment: 5 pages, 6 Figures, 17 reference